What is the Recurrence Rate After Operation of Cystitis Glandularis?
Cystitis glandularis is a rare proliferative lesion of the bladder mucosa without apparent causes. Most scholars believe that cystitis glandularis occurs when the transitional epithelium in the bladder encounters metaplasia under the long-term actions of chronic irritants and then transforms into the glandular epithelium. Cystitis glandularis may be associated with the following factors:
Lower urinary tract infections. Chronic bacterial infections of the bladder, especially gram-negative bacterial infections, are closely associated with cystitis glandularis. Long-term and frequent bacterial infections may be an essential factor in transforming chronic cystitis into cystitis glandularis.
Lower urinary tract obstruction or dysfunction. Non-fluent urine flow or the possibility of backward flow caused by lower urinary tract obstruction and dysfunction due to various factors, such as prostatic hyperplasia, neurogenic bladder, etc., will decrease urine flushing. The residual rine easily promotes the breeding and reproduction of bacteria.
Other factors. Long-term and chronic stimulation of bladder stones, polyps, tumors, catheterization, and foreign bodies can destroy the bladder mucosa, thus conducive to bacterial infections.
The main clinical manifestations of cystitis glandularis are: recurrent frequent urination, increased urgency in urination, pain during urination, increased urine at night, incontinence, enuresis, discomfort in the superior pubic area and perineum, swelling, and the feeling of bearing down in the lower abdominal, painful intercourse, reduced urine volume and hematuria. Many people with cystitis glandularis opt for surgeries.
Is operation effective for treating cystitis glandularis? What is the rate of recurrence after the operation of cystitis glandularis?
Cystitis glandularis is a disease involving the urinary system that, if left untreated, can lead to an increased risk of bladder cancer. The surgical treatment of cystitis glandularis is performed by local urethral mucosal resection. The disease can be cured entirely after excising the tissues and mucosas of the local lesions and assisting irrigation of the bladder and chemotherapy after surgery.
However, local recurrence of cystitis glandularis may occur under the induction or interference of certain factors. According to statistics, the recurrence rate of patients with cystitis glandularis after surgery is 30%~50%, and within half a year is 60% and 95% within a year. The recurrence rate is high after surgery.
Therefore, it is usually necessary to cooperate with injecting drugs into the bladder to optimize the efficacy of surgical treatments for cystitis glandularis, reducing the recurrence rate of cystitis glandularis after surgery as much as possible. However, drug injections do not entirely prevent the recurrence of cystitis glandularis.
Transurethral plasma kinetic electroresection for cystitis glandularis combined with bladder perfusion chemotherapy is currently the best method of Western medicine for cystitis glandularis.
The recurrence rate of cystitis glandularis can be reduced to 6%~7% with this method, and the rate of developing cancer can be reduced to 1%. However, postoperative bladder perfusion chemotherapy is unsuitable for all patients, and it will also bring other adverse effects due to the side effects of drugs and operational injuries.
Patients with cystitis glandularis do not have to choose surgical treatment. Patients with small lesions and mild frequent urination symptoms can take conservative medication, as operations can cause significant damage to the human body.
Only those with large lesions and severe symptoms of frequent urination require surgery. However, surgery can only help remove the lesions locally rather than cure the disease completely.
In addition to surgery, patients can also choose to:
I. Take herbal medicine as a conservative treatment of cystitis glandularis. It is recommended to choose Diuretic and Anti-inflammatory Pills. It can effectively kill all kinds of pathogenic bacteria and eliminate inflammation. It has the effect of promoting blood circulation, removing blood stasis, promoting the circulation of Qi, and relieving pain, thus stimulating blood circulation in the urinary and reproductive system to alleviate pain in the local areas.
Its effect of facilitating urination and treating strangurtia can help patients timely discharge bladder inflammatory secretions, thus reducing bladder irritation. In addition, the Diuretic and Anti-inflammatory Pill also have the effect of anti-hyperplasia, anti-fibrosis, and anti-calcification. It can dredge glands and eliminate follicles, effectively eliminating and preventing the papillary, leafy, follicular mixture in patients with cystitis glandularis and its recurrence.
II. Medication. Medication for cystitis glandularis is mainly divided into anti-infection therapy and the treatment of dribble urination.
Anti-infection therapy: antibiotics are generally used for improvement, and specific antibiotic types must be determined according to bacterial culture.
The treatment of dribble urination: for dribble urination, α receptor blockers are commonly used clinically to improve it.
II. Daily conditioning. First of all, the patient must be mentally relaxed because dribble urination is a benign lesion that will not induce cancer without treatment. Ten years ago, cystitis glandularis was treated by perfusion or electroresection. Now, after follow-up, it is found that many cases do not show many trends of cancer.
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